hrp0086p1-p811 | Syndromes: Mechanisms and Management P1 | ESPE2016

Correlations between Prepubertal and Pubertal Estrogen Levels and Final Height Out-Come in Growth Hormone (GH) Treated Boys with Silver Russell syndrome

Kvernebo-Sunnergren Kjersti , Ankarberg-Lindgren Carina , AEkesson Karin , Dahlgren Jovanna

Background: Children with Silver Russell syndrome (SRS) suffer from severe intrauterine growth retardation. During infancy, short stature and delayed bone maturation are common features. A majority of these children initially have a good growth response to GH treatment. A catch-up period of skeletal maturation is often seen in early puberty. Later in puberty poor height acceleration may be seen.Objective and hypothesis: The objective of this study was to...